ഐസോനിയാസിഡ്
ദൃശ്യരൂപം
Clinical data | |
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Trade names | Hydra, Hyzyd, Isovit, other |
Other names | isonicotinic acid hydrazide, isonicotinyl hydrazine, INHA |
AHFS/Drugs.com | monograph |
MedlinePlus | a682401 |
Routes of administration | by mouth, intramuscular, intravenous |
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Pharmacokinetic data | |
Protein binding | Very low (0–10%) |
Metabolism | liver; CYP450: 2C19, 3A4 inhibitor |
Elimination half-life | 0.5–1.6h (fast acetylators), 2-5h (slow acetylators) |
Excretion | urine (primarily), feces |
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DrugBank | |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.000.195 |
Chemical and physical data | |
Formula | C6H7N3O |
Molar mass | 137.139 g/mol |
3D model (JSmol) | |
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ക്ഷയരോഗത്തിന് നിലവിലുള്ള മരുന്നുകളിൽ ഒന്നാണ് ഐസോനിയാസിഡ്.[3] ക്ഷയത്തിന് ഇത് റിഫാംപിസിൻ, പൈറാസിനമൈഡ്, സ്ട്രെപ്റ്റോമൈസിൻ അല്ലെങ്കിൽ എത്താംബ്യൂട്ടോൾ എന്നിവയ്ക്കൊപ്പം ഉപയോഗിക്കുന്നു.
അവലംബം
[തിരുത്തുക]- ↑ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 Oct 2023.
- ↑ "Isoniazid". The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.
- ↑ "Isoniazid". The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.
ബാഹ്യ ലിങ്കുകൾ
[തിരുത്തുക]- Core Curriculum on Tuberculosis (2000) Division of Tuberculosis Elimination, Centers for Disease Control and Prevention
- See Chapter 6, Treatment of LTBI Regimens – Isoniazid::
See Chapter 7 – Treatment of TB Disease Monitoring – Adverse Reactions to First-line TB Drugs – Isoniazid::
See Table 5 First-Line Anti-TB Medications
- See Chapter 6, Treatment of LTBI Regimens – Isoniazid::
- Isoniazid Overdose: Recognition and Management Archived 2011-11-01 at the Wayback Machine. American Family Physician 1998 Feb 15